HM Pharma Water System&,Formulation System& Cleaning System
Follow up international standard European pharmacopoeia EP, US pharmacopoeia USP etc, comply with WHO
GMP, EU
cGMP, US FDA
regulations.
Pharmaceutical Water Production, Storage and Distribution System
Liquid Formulation Mixing,Filtering and Distribution System
Clean
and Sterilization System,
HM Pharmaceutical Water System
Application:
Purified water plant is composed of Reverse-Osmosis
system(RO) and with
pre-treatment
filtering system.The main RO system is from USA,
The
pipelines from RO system to user points is stainless steel
sanitary
level
in
accordance
with cGMP
regulations.It is suitable for production of purified water in pharmaceutical industry,
such as purified water for solid dosage, liquid dosage, semi-solid, SVP injectable dosage,
LVP
I.V. solution,
dialysis
etc.Technical Process Flow Chart
Raw water tank-Source
water
pump-Mechanical Sand Filter-Active Carbon Filter- Fine filter-High-pressure Pump- 1 or 2 RO System-CIP Unit
Reverse Osmosis RO system:
Separate
other objects
from water
under
high
resolution
infiltration by
pressures
through
RO
membrane.It
can
effectively
eliminate
the
dissolved
salt
water,
colloid,
microbiology,
heavy
metals,
organic
matter,
pyrogen,
virus
and
germ
etc.PW quality standard:
CP2010, European Pharmacopeia
EP6.Model: HM PW-2RO-0.5, 1, 2,3,4,5,10,20,30
Capacity: 0.5, 1, 2,3,4, 5,10,20, 30 T/h
Siemens PLC
and Touch Screen Automatic Control System With Online Conductivity Meter.
Option:
O-1.Heat Exchanger
O-2. Chemical Dosing system to feed chemicals to balance the PH
O-3. Water Softener to reduce the hardness of in-feed water
O-4. Electro De-ION( EDI) System
for HPW or UHPW.
Conductivity: <1.3uS/cm(25ºC), as per USP32 US Pharmacopeia, EDI
Features:
1. Continuous production, good quality and stable water, low cost;
2. No waste water, no use acid/alkali chemicals, saving water and no pollution.3. Compact structure, small land area; simple operation, simple routine maintenance,
low labor intensity;
O-5. Ultra-Filtering System UF:
use EDI+UF to make WFI.Ultra-micro-filtration is advanced membrane separation technology, using porous materials blocking ability to remove the certain impurity particles in water by physical interception way. This process operate in normal temperature, no phase change, does not produce secondary pollution.
HM DW series Multi-Column Distill Water Plant
Usage: distill purified water to
get distilled water to
match injection requirements
, also generate pure steam in some times.Suitable: water for injection (WFI), pyrogen free
Working principle: feed purified water into tube, steam evaporate
then
cooling water condense it, repeatedly pass multi-column tubes,
final obtain distill water.structure 1. Three-stage steam-water separation
structure;
structure 2. Internal spiral steam-water separation structure;
structure 3. External spiral steam-water separation structure.Quality: endotoxin content≤0.25 EU/ml; conductivity≤1 us/cm (20ºC)
conform to USP and EU relative regulation.Model difference: HM DW-III series, three
columns,three distillation effects;
HM DW-IV series, four effects, save about 23% energy, 40%water
HM DW-V series, five effects, save about 20% energy, 58%water
HM DW-VI series, six effects, save about 17% energy, 77%water
Model: HM DW- (III/IV)100/ 200/ 300/ (IV/V)500/750/ (V/VI)1000/ 1500/ 2000/ 3000/ 4000/5000
Capacity: at 3 bar
inlet steam (143ºC),
WFI:100/200/300/500/750/1000/1500/2000/3000/4000/5000 l/h
Pure steam:20/40/60/100/150/200/300/400/600/800/1000kgs/h
HM PSG series Pure Steam Generator
Usage: use
industrial steam from boiler or electrical
heating to generate pure steam.It consists of feeding water pump ,pre-heater column,tube type evaporator,water and steam separation system,defogger and control system.Suitable: cleam steam for the disinfections and sterilization (SIP)of solution mixing tank,holding tanks,
pipelines ,water user points,apparatus and tools
etc.Model: HM SG-100,200,300,500,750,1000,1500,2000,2500,3000,4000,5000
Capacity: 100,200,300,500,750,1000,1500,2000,2500,3000,4000,5000kgs/h
Options
Double Tubes Sheet(DTS) structure.SIEMENS PLC and Touch Screen Control System.Europe CE stangard and CERTIFICATE.Chart recorder to record temperatures.Can be designed for 4-6 bar etc.