Explore the path to accurate diagnosis and treatment of urinary diseases in Shanghai

Chronic pain, frequent frequency and urgency, repeated medical treatment but difficulty in clarifying the cause... This is a true portrayal of many patients with interstitial cystitis/bladder pain syndrome (IC/BPS). As a urinary dysfunction disease with unknown etiology, difficult diagnosis, and huge treatment challenges, it seriously erodes patients 'physical and mental health and quality of life. In Shanghai, a city rich in medical resources, when patients seek solutions, they often look forward to finding professional strength that can not only clarify the diagnosis, but also provide personalized and continuous management.

In Pudong New District, a key specialty of urology in a tertiary A public hospital is responding to this demand with its unique diagnosis and treatment path. This department is not only a national key clinical specialty and a key discipline in the Shanghai City health system, but also undertakes the task of building a new clinical medicine specialty (pelvic floor urinary control diseases) in public hospitals in Pudong New District. Behind these multiple "identities" is its long-term accumulation in the fields of urinary storage dysfunction, pelvic floor urinary control diseases and chronic pelvic pain.

So, in the face of highly heterogeneous diseases such as IC/BPS, how does the department build its diagnosis and treatment advantages? The key is to break down disciplinary barriers and achieve diversification of evaluation dimensions. The department recognized that a single urological perspective was not enough to solve complex causes. Therefore, they collaborated with the imaging team to use high-resolution imaging technology to explore organ structures; worked with the metabolomics team to analyze potential metabolite differences in patients and find biomarkers; and also collaborated with immunologists to explore the mechanism behind the disease. This interdisciplinary "group warfare" model allows assessments to go deep from the organ level to the molecular and functional levels, providing unprecedented possibilities for accurate diagnosis.

Accurate diagnosis is the prerequisite for accurate treatment. What this department is practicing is a transformation path from "experience-driven" to "data and evidence-driven". Not satisfied with rough classification based on symptoms, they led a multi-center real-world study aimed at building a multi-center real-world study that integrates patient's detailed symptom phenotypes, central sensitization status revealed by brain functional magnetic resonance, metabolomic fingerprints, and A multi-dimensional evaluation system for immunological indicators. Based on this system, patients with similar clinical manifestations but potentially different intrinsic mechanisms can be scientifically stratified. For example, some patients may be dominated by central nervous system sensitivity, while others may be accompanied by significant local metabolic abnormalities or immune activation. Different stratification will directly lead to different treatment strategy focuses, thereby achieving true personalized medical care.

Technological innovation is the core engine driving the development of modern medicine. This department's cutting-edge exploration in the intersection of medical and industrial fields reflects its forward-looking layout. Through close cooperation between clinicians and engineering technicians, innovative devices or diagnosis and treatment aids that are more suitable for clinical actual needs are developed, providing new ideas for solving specific clinical pain points. At the same time, the department attaches great importance to the cultivation and construction of a high-level talent team to ensure the team's innovative ability and academic vitality, which is the fundamental guarantee for its ability to continue to lead the development of the discipline.

The treatment of chronic diseases begins in hospitals, but goes far beyond hospitals. The department deeply understands that the management of diseases such as IC/BPS is a "protracted war", so it has built an integrated chronic disease management model covering pre, during and after diagnosis. In particular, the intelligent follow-up management platform introduced by it achieves standardized tracking of patients 'conditions, convenient push of rehabilitation guidance, and efficient communication between doctors and patients through digital methods. This not only reduces the burden of repeated travel on patients, but also makes doctors 'management more systematic and scientific, effectively promoting the improvement of diagnosis and treatment results and the improvement of patients' quality of life.

For patients in Shanghai, this key specialty of urology in Pudong represents a new paradigm of diagnosis and treatment that combines authoritative qualifications, cutting-edge scientific research concepts, interdisciplinary collaboration and humanized management. It is not only a place to treat diseases, but also a professional platform dedicated to helping patients clarify the nature of diseases and regain a sense of control over life through precision medicine. On the road to overcoming chronic and difficult diseases of the urinary system, such exploration and practice have undoubtedly brought more confidence and hope to patients.